The SS Republic's cargo of patent medicines included a consignment of Frederick Brown's Essence of Jamaica Ginger. Over 30 bottles were recovered from the wreck site, all empty of their original formula. When the ship sank in October 1865, Brown's product had been available to the public for over four decades. One of several Jamaica Ginger brands touted as a cure for various stomach ailments, the concoction is said to have contained a high alcoholic content, not uncommon among popular remedies of the era.
Following Brown's death in 1866, his son Fred Jr. assumed control of the company located in Philadelphia. City directories confirm the company remained in existence in 1917, Brown's famous preparation having survived on the market for nearly a century.